New research finds Diabetics have increased oral bone loss

New research finds Diabetics have increased oral bone loss

Oral Health News and trends that should affect your office procedures

Don’t fall into the set it and forget it trap of office routines. I get it, the idea of going to back new patient paperwork, revising it every time you want to reflect new findings in oral health can seem daunting. Yet, this step may be imperative in assisting your team’s early intervention strategies for patients’ bone health.

I’d like to bring your attention to the recent University of Pennsylvania study that links diabetics to excessive dental bone loss. It may make you consider revising your Dental Medical history intake forms or system of monitoring high-risk patients much sooner than later. Thus, supporting a system that flags at risk patients for close monitoring will allow your team to intercept issues before further degradation takes place.

“Up until now, there had been no concrete evidence that diabetes affects the oral microbiome,” said Dana Graves, senior author on the new study and vice dean of scholarship and research at University of Penn School of Dental Medicine. “But the studies that had been done were not rigorous.” Specifically, the Penn study finds that Diabetes causes the shift in oral microbiome that changes pathogenicity and fosters periodontitis. The research, published in the journal Cell Host & Microbe, last month not only showed that the oral microbiome of mice with diabetes shifted but that the change was associated with increased inflammation and bone loss.

diabetic dental bone xray

Interestingly, diabetic rats had increased inflammation and a more persistent inflammatory response following ligature-induced periodontal disease. Typically resulting in more prolonged osteoclast formation and activity, greater loss of attachment due to increased production of matrix metalloproteinases (Ryan et al., 1999), and diminished new bone formation. Diabetes-enhanced apoptosis of bone-lining and PDL cells may contribute to the latter.

Here at Synergy Specialist, our Oral Surgeons, Periodontists, and Endodontists are keenly aware of the latest research in the field. They educate doctors and patients in how to identify any signs of trouble ahead for patients. These trends and concerns are rapidly communicated through our robust network to ensure we are doing the best for all patients.

“Diabetes is one of the systemic disease that is most closely linked to periodontal disease, but the risk is substantially ameliorated by good glycemic control,” Graves said. He explains that vigilant oral hygiene can further reduce any risks of oral bone loss associated with diabetes. By setting up a system to ensure the extra needs of your diabetic patients are met, staff will be able to easily continue educating and communicating any concerns sooner than ever before.



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* E Xiao, Marcelo Mattos, Gustavo Henrique Apolinário Vieira, Shanshan Chen, Jôice Dias Corrêa, Yingying Wu, Mayra Laino Albiero, Kyle Bittinger, Dana T. Graves. Diabetes Enhances IL-17 Expression and Alters the Oral Microbiome to Increase Its Pathogenicity. Cell Host & Microbe, 2017; 22 (1): 120 DOI: 10.1016/j.chom.2017.06.014
* University of Pennsylvania. “Diabetes causes shift in oral microbiome that fosters periodontitis, Penn study finds.” ScienceDaily. ScienceDaily, 12 July 2017.

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